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目的探讨卡托普利联合双氢克尿噻治疗原发性高血压患者的临床疗效。方法将100例原发性高血压患者随机分为两组,每组50例。观察组采用卡托普利联合双氢克尿噻治疗,对照组只用双氢克尿噻。治疗时间均为8周,观察治疗前后患者的血压变化。结果单用双氢克尿噻组有效率为70%,卡托普利与双氢克尿噻合用组有效率为94%,两组差异有统计学意义(P<0.01)。结论卡托普利联合双氢克尿噻治疗原发性高血压的效果较单用双氢克尿噻好。
Objective To investigate the clinical efficacy of captopril combined with hydrochlorothiazide in patients with essential hypertension. Methods 100 patients with essential hypertension were randomly divided into two groups, 50 cases in each group. Observation group using captopril combined with hydrochlorothiazide therapy, the control group only with hydrochlorothiazide. The treatment time was 8 weeks, observed before and after treatment of patients with changes in blood pressure. Results The effective rate was 70% in the single hydrochlorothiazide group and 94% in the captopril group and the hydrochlorothiazide group, the difference between the two groups was statistically significant (P <0.01). Conclusions Captopril combined with hydrochlorothiazide is superior to hydrochlorothiazide alone in the treatment of essential hypertension.