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硝酸甘油应用于治疗心血管疾病已有一百多年的历史,目前硝酸甘油以多种形式使用,如舌下含片、皮肤软膏,长效膜剂和长效口服片,静脉应用仅仅有15年历史,而这种给药途径在几方面都有极好的评价。商品的硝酸甘油静脉注射液在1981年9月已生产使用,纽约Rochester市斯特朗纪念医院的药剂科则自己生产硝酸甘油静脉注射液,代替商品制剂。该医院药剂科使用1份硝酸甘油和9份乳糖的粉末安瓿,称量后置于12升的玻璃烧
Nitroglycerin has been used for more than 100 years in the treatment of cardiovascular diseases. At present, nitroglycerin is used in various forms such as sublingual tablet, dermal ointment, long-acting film, and long-acting oral tablet. There are only 15 Year history, and this route of administration is excellent in several ways. The commercial nitroglycerin IV solution was manufactured in September 1981 and the pharmacy division at Strum Memorial Hospital in Rochester, NY, produces its own nitroglycerin IV solution instead of the commercial formulation. The pharmacy department of the hospital uses 1 part of powder ampoule of nitroglycerin and 9 parts of lactose, weighing it and placing it in a glass jar of 12 liters