Sweet′s综合征是一种急性发热性、伴有嗜中性粒细胞增多的皮肤病,约20％患者可并发各种恶性肿瘤。自1964年Sweet医师首次介绍以来,文献已报道几百例类似的病例,其中近80例伴有恶性肿瘤。在伴发的各种恶性肿瘤中,以血液系统恶性肿瘤为最多见,其次为实体瘤,如泌尿生殖系恶性肿瘤和乳癌等。本文就Sweet′s综合征近几年的研究进展作一简要综述。 Sweet’s syndrome is an acute febrile skin disease associated with neutrophilia. About 20% of patients have concurrent malignancies. Since Dr. Sweet first introduced in 1964, several hundred similar cases have been reported in the literature, of which nearly 80 are associated with malignancies. Of the various malignant tumors associated with hematological malignancies are the most common, followed by solid tumors, such as genitourinary malignancies and breast cancer. This article reviews the progress of Sweet’s syndrome in recent years.