目的　探讨风湿性心脏病患者手术后妊娠的可能性、时机及孕期抗凝治疗问题。方法　对 1992年12月至 2 0 0 3年 5月收治的 37例风湿性心脏病手术后妊娠的患者进行回顾性分析。结果　风湿性心脏病术后妊娠 37例 ,足月妊娠 35例 ,新生儿 35例存活无畸形 ;2例因胎死宫内终止妊娠 ,无孕产妇死亡。结论　风湿性心脏病术后心脏功能Ⅰ～Ⅱ级能使妊娠成功 ,但要选择适当的时机 ;换瓣术后孕期口服香豆素类抗凝剂能有效防止血栓形成 ,但其安全性尚待进一步研究 Objective To investigate the possibility of pregnancy after surgery in patients with rheumatic heart disease, timing and anticoagulant therapy during pregnancy. Methods A retrospective analysis was performed on 37 patients with postoperative pregnancy after rheumatic heart disease admitted from December 1992 to May 2003. Results 37 cases of postoperative pregnancy rheumatic heart disease, 35 cases of full-term pregnancy, 35 newborns survived without deformity; 2 cases of termination of pregnancy due to fetal death, no maternal death. Conclusions The cardiac function Ⅰ ~ Ⅱ of rheumatic heart disease can make the pregnancy successful, but the proper timing should be selected. The oral administration of coumarin anticoagulant during the postoperative period can effectively prevent the thrombosis, but its safety is yet to be determined further research