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目的分析静脉曲张性溃疡的临床表现、细菌感染和药敏特征。方法对2011年1月—2015年1月确诊的92例静脉曲张性溃疡住院患者的临床资料进行回顾性分析。结果92例静脉曲张性溃疡患者中男68例,女24例,平均年龄61岁,静脉曲张平均病程15年,溃疡平均病程3.47年,溃疡平均面积10.37 cm2。41例细菌培养阳性患者中金黄色葡萄球菌占26.8%(11例),铜绿假单胞菌占21.9%(9例)。金黄色葡萄球菌对青霉素100%耐药,铜绿假单胞菌对医院常用抗生素如氨苄西林、头孢曲松、头孢呋辛钠等耐药。结论静脉曲张性溃疡好发于老年男性,病程和住院时间长,溃疡面感染细菌以铜绿假单胞菌、金黄色葡萄球菌为主,根据细菌分布及药敏分析,需要高度重视这些细菌种类的演变和耐药。
Objective To analyze the clinical manifestations, bacterial infections and susceptibility characteristics of varicose ulcer. Methods The clinical data of 92 inpatients with varicose ulcer diagnosed from January 2011 to January 2015 were analyzed retrospectively. Results Among the 92 patients with varicose ulcer, 68 were male and 24 were female, with an average age of 61 years. The average duration of varicose vein was 15 years. The average course of ulcer was 3.47 years. The average area of ulcer was 10.37 cm2. Staphylococcus accounted for 26.8% (11 cases), Pseudomonas aeruginosa accounted for 21.9% (9 cases). Staphylococcus aureus 100% resistant to penicillin, Pseudomonas aeruginosa commonly used antibiotics in hospitals such as ampicillin, ceftriaxone, cefuroxime sodium resistance. Conclusions Varicose ulcer occurs in older men with longer duration and length of hospital stay. The bacteria in the ulcer surface are mainly Pseudomonas aeruginosa and Staphylococcus aureus. According to the bacterial distribution and drug susceptibility analysis, it is necessary to attach great importance to these bacterial species Evolution and resistance.