介绍了黏膜给药原位凝胶的优点、分类、常用聚合物,以及原位凝胶在各黏膜给药部位的应用情况。作为一种新型的药物传递系统,黏膜给药原位凝胶虽还存在一些技术难点有待攻克,但它结合了原位凝胶制剂和黏膜给药途径双重优势,是一个很有发展潜力的药物传递系统,尤其在中药新剂型的研究方面有着广阔的发展前景。 The advantages, classification, commonly used polymers, and the application of in situ gels to mucosal administration sites were introduced. As a new drug delivery system, there are some technical difficulties to be overcome in mucosal administration of in-situ gel, but it combines the advantages of in-situ gel preparation and mucosal administration and is a promising drug Delivery system, especially in the study of new formulations of traditional Chinese medicine has broad prospects for development.