东南亚卵形红细胞症(Southeast Asianovalocytosis,SAO)在西太平洋疟疾流行区的发生率高达人口的35％,它是由第17号染色体的红细胞膜带3基因缺失27对碱基引起的。带3是红细胞主要的膜蛋白,起维持细胞形态、增加血液携带CO_2能力的作用,在体外可介导原虫寄生性红细胞的细胞粘附作用。本文作者于1993年10月—1996年2月在巴布亚新几亚北岸的疟疾高发区的Madang医院儿科选取住院疟疾病例进行前 Southeast Asian ova disease (Southeast Asianovalocytosis, SAO) in the western Pacific malaria prevalence rate of up to 35% of the population, which is caused by the deletion of 27 base pairs on chromosome 17 red blood cell membrane 3 gene. Band 3 is the major membrane protein of erythrocytes, which plays a role in maintaining the cell morphology and increasing the ability of blood to carry CO 2, and can mediate the cell adhesion of parasite erythrocytes in vitro. The author of this paper was selected from a pediatric malaria hospital in Madang Hospital in the malaria-prone area of ​​northern coast of Papua New Guinea from October 1993 to February 1996