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目的探讨降钙素原(PCT)和C反应蛋白(CRP)检测在小儿急性呼吸道感染中的临床意义。方法选择急性呼吸道感染患儿70例和健康儿童50例,分别测定他们的降钙素原和C反应蛋白。结果细菌感染组降钙素原和C反应蛋白均显著高于病毒感染组和正常对照组(P<0.01),但病毒感染组和正常对照组比较差异无显著性(P>0.05)。结论小儿患急性呼吸道感染时检测其体内降钙素原和C反应蛋白对鉴别细菌和病毒感染,指导临床合理用药有重要的意义。
Objective To investigate the clinical significance of procalcitonin (PCT) and C-reactive protein (CRP) detection in children with acute respiratory infection. Methods 70 cases of children with acute respiratory infection and 50 healthy children were selected and their procalcitonin and C-reactive protein were measured. Results The levels of procalcitonin and C-reactive protein in bacterial infection group were significantly higher than those in viral infection group and normal control group (P <0.01). However, there was no significant difference between viral infection group and normal control group (P> 0.05). Conclusion Pediatric patients with acute respiratory infection in the detection of procalcitonin and C-reactive protein in identifying bacterial and viral infections, clinical rational use of medication is of great significance.