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再生障碍性贫血(再障)发病率较高,多见于青年,治疗效果较差。近年来,我们研究发现再障与免疫损伤有密切关系。我们对成人再障患者做了IgG、IgA和IgM的测定,现将测定结果与再障之间关系做一分析。 1 对象与方法:①对象:25例再障患者诊断标准按1989年《全国再障专题座谈会修订的再障诊断和分型标准》。男17例、女8例,年龄14岁～38岁,均为原发性再障。临床表现主要为贫血、出血,以牙龈、鼻、皮肤粘膜出血及阴道流血为主,感染,倦怠;气短22例,25例均无淋巴结及肝脾肿大。实验室检查:红细胞数(100～150)×10~(12)/L15例,(150—200)×10~(12)/L10
Aplastic anemia (aplastic anemia) a higher incidence, more common in young people, the treatment effect is poor. In recent years, we found that aplastic anemia and immune damage are closely related. We have done a determination of IgG, IgA and IgM in adults with aplastic anemia, now the results of the determination and the relationship between aplastic anemia do an analysis. 1 Subjects and Methods: ① Subjects: 25 cases of aplastic anemia patients diagnostic criteria by 1989 “National Astigmatism Symposium revised aplastic anemia diagnosis and classification criteria.” 17 males and 8 females, aged 14 to 38 years old, are primary aplastic anemia. Clinical manifestations mainly anemia, bleeding, gums, nose, skin and mucous membrane bleeding and vaginal bleeding, infection, fatigue; shortness of breath in 22 cases, 25 cases were no lymph nodes and hepatosplenomegaly. Laboratory tests: The number of red blood cells (100 ~ 150) × 10 ~ (12) / L in 15 cases, (150-200) × 10 ~ (12) / L10