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目的 :分析比较99mTc -MIBI(甲氧基异丁基异腈)乳腺显像与钼靶X线摄影法对乳腺肿块的临床诊断价值。方法 :40例单侧乳腺肿块患者 ,包括良性病变29例 ,恶性病变11例 ,在1周内同时接受99mTc -MIBI乳腺显像和钼靶X线摄影检查。钼靶X线片结合放大镜观察钙化点的情况分析 ,99mTc -MIBI显像取感兴趣区(ROI) ,求出肿块与正常组织中放射性比值(T/NT)。结果 :99mTc-MIBI显像T/NT放射性比值 ,恶性为1 98±0 22(n=12) ;良性为1 16±0 10(n=28) ;两者有显著性差异(P<0 01)。99mTc-MIBI显像与钼靶X线摄影法诊断乳腺癌的灵敏度和特异性分别为83 3%、92 8%和90 9 %、24 1%。结论 :钼靶X线摄影发现乳腺恶性病变敏感性高而特异性低 ;99mTc-MIBI显像对乳腺肿块诊断特异性和准确性明显优于钼靶X线摄影 ,两种影像方法各有所长 ,如果结合应用 ,可提高诊断的准确性
Objective: To analyze the clinical value of 99mTc-MIBI (methoxyisobutylisonitrile) breast imaging and mammography in the diagnosis of breast masses. Methods: Forty patients with unilateral breast masses, including 29 benign lesions and 11 malignant lesions, underwent both 99mTc-MIBI breast imaging and mammography in one week. Molybdenum target X-ray combined with a magnifying glass to observe the calcification point analysis, 99mTc -MIBI imaging area of ?? interest (ROI), obtained tumor and normal tissue radioactivity ratio (T / NT). Results: The ratio of T / NT radioactivity in 99mTc-MIBI imaging was 1 98 ± 0 22 (n = 12) and benignity was 116 ± 0 10 (n = 28), both of which were significantly different (P <0.01 ). The sensitivity and specificity of 99mTc-MIBI imaging and mammography in diagnosing breast cancer were 83.3%, 92.8%, 90.9% and 24.1%, respectively. Conclusion: Mammography has high sensitivity and low specificity in the diagnosis of malignant breast lesions. The specificity and accuracy of 99mTc-MIBI imaging in the diagnosis of breast masses is better than that of mammography. The two imaging methods have their own advantages , If used in combination, can improve the diagnostic accuracy