男,24岁。渐起下行性水肿,尿少(200～300ml/d),头昏,乏力,恶心,呕吐两年余。尿蛋白++～++++,有红,白细胞及颗粒管型;偶见肉眼血尿。外院诊断“慢性肾炎肾病综合征”,经激素治疗症状缓解,但每逢感冒或停服激素后即复发。体查:体温37.5℃,血压120/100,颜面水肿,咽充血;双肺清晰,心率78次,无杂音;腹软,肝脾未及;双下 Male, 24 years old. Gradually descending edema, oliguria (200 ~ 300ml / d), dizziness, fatigue, nausea, vomiting more than two years. Urinary protein ++ ~ ++++, red, white blood cells and granular tube type; occasionally gross hematuria. Outside the hospital diagnosis of “chronic nephritic nephrotic syndrome”, hormone therapy to alleviate the symptoms, but whenever the cold or stop taking the hormone that relapse. Physical examination: body temperature 37.5 ℃, blood pressure 120/100, facial edema, pharyngeal congestion; clear lungs, heart rate 78 times, no noise; abdominal soft, liver and spleen not; double