我们于1979年以大剂量异烟肼静脉滴注治疗结核性脑膜炎(简称“结脑”)10例。方法是:首次用异烟肼600毫克和氟美松10毫克加入10%葡萄糖溶液500毫升静滴,以后异烟肼按200毫克/日的量递增,直至总量达2克为1疗程,同时每日日服异烟肼0.4克及肌注链霉素1克。必要时,间歇3～7天再行第2疗程。结果,4例出现癫痫样发作,现报告如下。 We in 1979 with high-dose isoniazid intravenous infusion of tuberculous meningitis (referred to as “knot brain”) 10 cases. The method is: For the first time with isoniazid 600 mg and dexamethasone 10 mg added 10% glucose solution 500 ml intravenous infusion, after isoniazid 200 mg / day volume increase until the total amount of 2 grams for a course of treatment, at the same time Daily service isoniazid 0.4 g and streptomycin 1 g intramuscularly. If necessary, intermittent 3 to 7 days before the second course of treatment. Results, 4 cases of epileptic seizures, are as follows.