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目的探讨脂蛋白α检测对糖尿病足诊断的价值。方法以我院2009年1月-2012年12月间27例糖尿病足病患者为研究对象,将27例未患有糖尿病足病的糖尿病患者作为对照,比较两组患者在糖尿病相关生化指标和糖尿病足病相关脂蛋白指标间的差异。结果两组患者在TG、TC、HEL-C、LDL-C、FPG、ApoA、ApoB、ApoE含量方面无显著差异,观察组脂蛋白α浓度高于对照组,差异有统计学意义(P<0.05)。在Logistic多因素回归分析中,对糖尿病患者是否发生糖尿病足病有较为显著的影响是患者的性别、糖尿病病程及脂蛋白α的含量。结论脂蛋白α可以作为糖尿病足病诊断的重要指标。
Objective To investigate the value of lipoprotein α in the diagnosis of diabetic foot. Methods Twenty-seven patients with diabetic foot disease from January 2009 to December 2012 in our hospital were enrolled in this study. Twenty-seven patients with diabetes who did not have diabetic foot disease were selected as controls. The biochemical indexes and diabetes mellitus Differences between the podopathies-related lipoprotein indexes. Results There was no significant difference in the contents of TG, TC, HEL-C, LDL-C, FPG, ApoA, ApoB and ApoE between the two groups. The level of lipoprotein α in the observation group was higher than that in the control group ). In Logistic multivariate regression analysis, there was a significant effect on whether diabetic foot disease occurred in patients with diabetes mellitus, the patient’s gender, duration of diabetes and lipoprotein α content. Conclusion Lipoprotein α can be used as an important index in the diagnosis of diabetic foot disease.