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目的:编制适合中国口腔癌患者的生活质量量表,并验证该量表信度和效度。方法:参照简明健康状况调查问卷(SF-36)和华盛顿大学头颈肿瘤生活质量量表(UW-QOL),并结合中国人群社会文化特点,编制郑州大学口腔癌患者生活质量量表(Zhengzhou University Oral Cancer-QOL,ZZU-QOL)。对271例患者进行调查后,采用SPSS19.0软件包中的t检验、相关分析、因子分析等方法对测试版量表信度和效度进行评价。结果:在重测信度方面,各领域和整个量表在2次测量之间的相关系数为0.86~1.00,均无显著差异。在同质信度方面,各个领域的Cronbach系数均大于0.6,显示测试版量表具有较好的信度。在结构效度方面ZZU-QOL、SF-36和UW-QOL量表经因子分析选出的前7个因子方差累计贡献率分别为69.3%、63.4%和66.5%。以SF-36和UW-QOL作为效标,其效标效果分别为0.768和0.634。ZZU-QOL量表能敏感地区分口腔癌患者术前与术后生活质量的差异。结论:ZZU-QOL具有较好的信度和效度,适用于中国口腔癌患者生活质量的测评。
Objective: To prepare a quality of life scale for patients with oral cancer in China and verify the reliability and validity of the scale. Methods: According to the questionnaire of simple health status (SF-36) and the University of Washington’s Head and Neck Cancer Quality of Life Scale (UW-QOL), and combined with the social and cultural characteristics of Chinese people, Zhengzhou University Oral Quality of Life Scale Cancer-QOL, ZZU-QOL). After investigating 271 patients, t-test, correlation analysis, factor analysis and other methods in the SPSS19.0 package were used to evaluate the reliability and validity of the test version of the scale. Results: In terms of test-retest reliability, the correlation coefficient between the two scales was 0.86 to 1.00 in all fields and the entire questionnaire, with no significant difference. In terms of homogeneity and reliability, the Cronbach coefficients in all fields are greater than 0.6, indicating that the beta scale has good reliability. In terms of structural validity, the cumulative contribution rates of the first seven factors selected by factor analysis from ZZU-QOL, SF-36 and UW-QOL scales were 69.3%, 63.4% and 66.5%, respectively. The effective standard effects of SF-36 and UW-QOL were 0.768 and 0.634 respectively. ZZU-QOL scale can differentiate the difference between preoperative and postoperative quality of life in patients with oral cancer. Conclusion: ZZU-QOL has good reliability and validity, which is suitable for the evaluation of quality of life of oral cancer patients in China.