超声波细胞基因导入是近年来才开发出来的一种新的物理方法。不过目前超声装置没有统一的标准,传统转导法通常是宏观体积的,不能做到特定细胞或者单个细胞的定向转导。基于微机电系统(MEMS)工艺设计制作的器件将超声波与微流控技术结合,能克服上述缺点。此外还具有样本用量少,经济节约、操作简便等优点,是基因转导发展的一个趋势。 Ultrasound cell gene transfer is a new physical method developed in recent years. However, there is no unified standard for ultrasound devices at present. Traditional transduction methods are usually macroscopic in size and can not perform targeted transduction of specific cells or individual cells. Devices based on micro-electromechanical systems (MEMS) processes are designed to combine ultrasonic and microfluidic technologies to overcome these shortcomings. In addition, it also has the advantages of less sample consumption, economic saving and simple operation, which is a trend of gene transduction.