大肠癌早期诊断水平有了明显的提高 ,获得治愈性切除的病例逐渐增加。 5年生存率达 40 %～ 5 0 % ,但复发率仍高达 30 %～ 5 0 %。如何预防和治疗大肠癌术后复发与转移是 2 1世纪亟待研究解决的课题。1　大肠癌复发和转移的类型　　切缘阳性或癌细胞在吻合口种植可导致吻合口复 The early diagnosis of colorectal cancer has been significantly improved, and the number of cases of curative resection has gradually increased. The 5-year survival rate is 40% to 50%, but the recurrence rate is still as high as 30% to 50%. How to prevent and treat postoperative recurrence and metastasis of colorectal cancer is a topic that needs urgent study and solution in the 21st century. 1 Types of colorectal cancer recurrence and metastasis Positive margin or cancerous cells in anastomosis can lead to anastomotic recurrence