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5 初始化疗 现在已有的选择包括:单用马法兰或环磷酰胺(加/不加强的松龙),也用两药联合化疗方案(包含烷化剂),治疗的目的是达到稳定 的疗效或平台期。VAD(长春新碱、阿霉素、地塞米松)和类似方案(包括 大剂量地塞米松但无烷化剂);这类方案之后常用大剂 量化疗联合干细胞解救。初始化疗的选择取决于诸如患者年龄、体能状况及是否 计划进行干细胞采集和大剂量化疗(HDT)等因素。
5 initial chemotherapy now available options include: single use of melphalan or cyclophosphamide (plus / without prednisolone), also with two drug combination chemotherapy (including alkylating agents), the purpose of treatment is to achieve a stable effect or Platform period. VAD (vincristine, doxorubicin, dexamethasone) and similar programs (including high-dose dexamethasone but no alkylating agent); these regimens are often followed by high-dose chemotherapy combined with stem cell rescue. The choice of initial chemotherapy depends on factors such as patient age, fitness status, and whether or not to plan stem cell harvest and high-dose chemotherapy (HDT).