血小板和凝血系统的激活常使妊娠过程复杂化并能导致明显的病状,一般认为触发机制是一种释放到母体循环中的胎儿产物,因此分娩后病可消退.久已认识到胎盘是凝血激酶的丰富来源,此种物质在妊娠凝血疾患的发病机制中起作用.羊水中也有丰富的凝血激酶,本文首次报导羊水中还存在血小板激活因子. Activation of platelets and the coagulation system often complicates the pregnancy process and can lead to significant symptoms, which are generally thought to trigger the release of fetal products into the maternal circulation, so that after childbirth, the disease subsides. It has long been recognized that the placenta is thromboplastin Rich source of such substances in the pathogenesis of coagulation disorders in pregnancy play a role in amniotic fluid is also rich in thromboplastin, the first report in this article, amniotic fluid platelet activating factor also exists.