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已知许多药可加重或诱发重症肌无力(MG),延迟肌松弛或引起肌无力综合征。包括许多抗菌素,抗风湿的、心血管的、抗惊厥和治疗精神病药物。除了直接作用于神经肌肉传递的一些药物外,尚有诱导产生自动抗体,抗乙酰胆硷受体蛋白,以及其他作用于脊髓反射或肌纤维本身的药物,因之也增加无力。最后一组,如苯二氮(艹卓)类,对神经肌肉安全因素降低的患者特别危险,如前角细胞病变,各
Many drugs are known to aggravate or induce myasthenia gravis (MG), delay muscle relaxation, or cause myasthenic syndrome. Includes many antibiotics, anti-rheumatic, cardiovascular, anticonvulsant and psychotropic drugs. In addition to acting directly on neuromuscular delivery of some drugs, there are also induced autoantibodies, anti-acetylcholine receptor protein, and other drugs acting on the spinal reflex or muscle fibers, which also increased weakness. The last group, such as benzodiazepines, is particularly dangerous for patients with reduced neuromuscular safety factors, such as anterior horn cytopathy,