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目的:观察中药益心汤对慢性充血性心力衰竭(CHF)患者血液N末端B型钠尿肽原(NT-proB-NP)水平的影响及与临床疗效间的关系。方法:实验对象为CHF病人60例,将其随机分为两组,对照组采用西医常规治疗,治疗组在西医常规治疗基础上加用中药益心汤,详细记录每位患者心功能程度,同时用干式免疫荧光定量检测NT-proBNP水平。结果:两组NT-proBNP水平均明显下降(P<0.01),其中治疗组较对照组更加明显(P<0.05)。结论:中药益心汤与常规西药共同使用治疗慢性充血性心力衰竭,疗效明显优于西药常规治疗。
Objective: To observe the effect of Yixin Tang on the level of N-terminal pro-B-NP in patients with chronic congestive heart failure (CHF) and its relationship with clinical efficacy. Methods: Sixty patients with CHF were randomly divided into two groups. The control group was treated routinely with western medicine. The treatment group was treated with traditional Chinese medicine Yixin Decoction on the basis of routine treatment of Western medicine. The degree of cardiac function in each patient was recorded in detail. At the same time NT-proBNP levels were quantified by dry immunofluorescence. Results: NT-proBNP levels were significantly decreased in both groups (P <0.01), of which the treatment group was more obvious than the control group (P <0.05). Conclusion: Traditional Chinese medicine Yixin Tang and conventional western medicine for the treatment of chronic congestive heart failure, the effect was significantly better than the conventional Western medicine.