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本文报告使用三类不同的降压药治疗原发性高血压的血脂改变,疗程均为六周。心得安组18例,治疗后 TG 显著增高,HDL 水平和 HDL/T-ch 显著降低,由于血脂改变的不利因素,同意不宜使用心得安作为第一线的降压药的观点。哌唑嗪组26例,治疗后 HDL 水平和 HDL/T-ch 值显著增高,T-ch、TG 和 BLP 均略低,硝苯吡啶组21例,治疗后 HDL 和 HDL/T-ch 增高。哌唑嗪组和硝苯吡啶组血脂的改变有利于防止动脉硬化,初步认为可作一线降压药。
This article reports the use of three different types of antihypertensive drugs for the treatment of essential hypertension, lipid changes, treatment are six weeks. Adrenaline in 18 cases, TG was significantly increased after treatment, HDL levels and HDL / T-ch was significantly reduced due to unfavorable factors of blood lipids, agree not to use propranolol as the first line of antihypertensive drugs point of view. HDL level and HDL / T-ch value were significantly increased after treatment in 26 cases of prazosin group, T-ch, TG and BLP were slightly lower, nifedipine group of 21 patients after treatment HDL and HDL / T-ch increased. Prazosin group and nifedipine group lipid changes help prevent atherosclerosis, initially considered as first-line antihypertensive drugs.