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研究北冬虫夏草多糖对人外周血单个核细胞（ＰＢＭＣ）分泌肿瘤坏死因子α（ＴＮＦ－α），生成可溶性白细胞介素２受体（ｓＩＬ－２Ｒ）及人外周血淋巴细胞（ＰＢＬ）分泌白细胞介素２（ＩＬ－２）的影响。结果表明：北冬虫夏草多糖在１０～５０ｍｇ·Ｌ－１浓度时，刺激单个核细胞分泌ＴＮＦ－α（Ｐ＜０．０５）。在０．１～１０ｍｇ·Ｌ－１浓度时，刺激单个核细胞生成ｓＩＬ－２Ｒ（Ｐ＜０．０５，Ｐ＜０．０１），且在一定浓度范围内ＴＮＦ－α及ｓＩＬ－２Ｒ水平随北冬虫夏草多糖浓度增加而升高；北冬虫夏草多糖对刀豆蛋白Ａ（ＣｏｎＡ）刺激的人外周血淋巴细胞分泌ＩＬ－２水平有明显促进作用（Ｐ＜０．０５）。
To study the secretion of tumor necrosis factor-α (TNF-α) by human cordyceps sinensis polysaccharides on human peripheral blood mononuclear cells (PBMC), to generate soluble interleukin 2 receptor (sIL-2R) and to secrete leukocytes from human peripheral blood lymphocytes (PBL). Effect of Su-2 (IL-2). The results showed that the polysaccharide of North Cordyceps sinensis stimulated the secretion of TNF-α from the mononuclear cells at the concentration of 10-50 mg·L-1 (P<0.05). At a concentration of 0.1 to 10 mg·L-1, sIL-2R was stimulated by mononuclear cells (P<0.05, P<0.01), and the levels of TNF-α and sIL-2R were associated with a certain concentration range. The concentration of polysaccharides in Cordyceps militaris was increased and increased; the polysaccharides of Cordyceps militaris significantly stimulated the secretion of IL-2 from human peripheral blood lymphocytes stimulated by ConA (Con A) (P<0.05).