人们通常认为,皮质醇的主要代谢部位是肝脏。而在先天性或获得性11-β-17羟类固醇脱氢酶缺陷的病人中研究提示,肾脏是人体产生可的松的主要器官。 诊断明确为肾脏疾病患者88例(38名女性)为实验组,各例肝功能检查正常。其中52例肾小球肾炎,12例返流性肾病,24例其它疾病如多囊肾、镇 It is generally believed that the main metabolic site of cortisol is the liver. However, studies in patients with congenital or acquired 11-beta-17 hydroxysteroid dehydrogenase deficiency suggest that the kidney is the major organ for cortisol production in humans. Eighty-eight patients (38 women) diagnosed as having kidney disease were selected as the experimental group, and their liver function tests were normal. 52 cases of glomerulonephritis, 12 cases of reflux nephropathy, 24 cases of other diseases such as polycystic kidney disease, town