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本文应用妊娠小鼠及其胎鼠肝脏细胞的姐妹染色单体互换及微核试验,探讨人参茎叶总皂甙是否诱发母、胎遗传物质的损伤。实验结果证实,人参茎叶总皂甙对孕鼠及其胎儿组织无诱变作用。
In this paper, the sister chromatid exchange and micronucleus test of liver cells from pregnant mice and their fetuses were used to investigate whether the total saponins of stems and leaves of ginseng could induce damage to the genetic material of mother and fetus. The experimental results confirmed that Ginsenosides have no mutagenic effect on pregnant rats and their fetal tissue.