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研制了一套探头末端直径为1mm的血管内扫频光学相干层析成像(IV-OCT)系统。为了确保探头内格林透镜的中轴线与安装在微型电机轴上的直角棱镜的中轴线对准,制作了尺寸匹配的塑料套管;将格林透镜插入塑料套管后与微型电机一同安装于聚四氟乙烯(PTFE)管中,制成了末端直径为1mm的探头。对光源自带的k-clock信号进行硬件滤波以去除其中的直流分量和谐波分量,提高了系统分辨率。对等波数域间隔重采样后的干涉光谱数据进行加窗、快速傅里叶变换(FFT)、取对数、背景去除后,将得到的多个轴向扫描(A-scan)数据进行坐标变换、重建,从而得到圆环显示的样品图像。实测系统纵向分辨率为11.8μm,横向分辨率为24μm,成像帧速为30frame/s。利用研制的IV-OCT系统,实现了管状白胶带、小葱葱管、藕、离体鸭血管样品的OCT成像。
A set of IV-OCT system with a 1mm diameter probe end was developed. In order to ensure that the central axis of the Green’s lens in the probe is aligned with the central axis of the right-angle prism mounted on the micro-motor shaft, a plastic sleeve with a matched size is manufactured. After the Green lens is inserted into the plastic sleeve, Fluorine Ethylene (PTFE) tube, a probe having a tip diameter of 1 mm was made. The k-clock signal from the light source is hardware-filtered to remove the DC and harmonic components and improve the system resolution. After the resampled interference spectral data in the interval domain of the equalizer is subjected to windowing, fast Fourier transform (FFT), the logarithm and the background are removed, and then a plurality of obtained A-scan data are subjected to coordinate transformation , Reconstructed, resulting in a sample image of the ring displayed. The measured system has a vertical resolution of 11.8μm, a horizontal resolution of 24μm and an imaging frame rate of 30frame / s. Using the developed IV-OCT system, OCT imaging of tubular white tape, onion, lotus root and isolated duck blood vessels was achieved.