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神经干细胞因具有高度自我更新能力、多潜能分化、低免疫原和迁移功能等特征[1],在脑卒中、神经变性等疾病的治疗中显示出良好的应用前景[2~4]。移植的干细胞可以替代缺失的神经细胞,向病灶区迁移分化并和周围组织建立突触联系[5],以达到治疗目的。但是,单独的干细胞分化为神经
Neural stem cells have shown promising applications in the treatment of stroke and neurodegenerative diseases due to their high self-renewal ability, multipotential differentiation, low immunogen and migration function [1]. Transplantation of stem cells can replace the missing nerve cells, to the lesion migration and differentiation and the establishment of synaptic connections with surrounding tissues [5], for therapeutic purposes. However, individual stem cells differentiate into nerves