角膜神经是眼表的重要结构,对于维持角膜正常结构和功能起着重要的作用。多种眼部手术(屈光手术、角膜移植术)、多种眼表疾病(单纯疱疹性角膜炎、干眼症)、全身疾病(糖尿病),乃至长期使用滴眼药物都将影响角膜神经的形态和功能。正常角膜神经的缺失将导致角膜的营养不良及代谢障碍。从角膜神经的解剖、生理与病理、创伤愈合与修复、与角膜神经异常有关的眼病、神经再生以及问题与展望等六个部分进行综述,便于更好地理解角膜神经的构造和功能,为更好地开展保护角膜神经工作做一铺垫。 Corneal nerve is an important ocular surface structure, plays an important role in maintaining the normal structure and function of the cornea. A variety of eye surgery (refractive surgery, corneal transplantation), a variety of ocular surface diseases (herpes simplex keratitis, dry eye), systemic disease (diabetes), and even long-term use of eye drops will affect the corneal nerve drugs Form and function. The loss of normal corneal nerves leads to corneal malnutrition and metabolic disorders. This review summarizes the anatomy, physiology and pathology of the corneal nerve, wound healing and repair, ocular diseases related to corneal nerve abnormalities, nerve regeneration and the problems and prospects so as to better understand the structure and function of the corneal nerve. Good protection of the corneal nerve to do a bedding.