论文部分内容阅读
目的观察冠心平抗心肌缺血作用。方法采用犬左冠脉前降支第一分支下方2mm处结扎法制备心肌缺血模型,以复方丹参滴丸为阳性对照药,观察冠心平是否具有保护缺血心肌、减少心肌坏死面积、减少心肌酶CK、CK-MB、LDH释放量的作用。结果缺血心肌坏死面积明显减小,CK、CK-MB、LDH释放量明显减少。结论冠心平对犬急性心肌缺血具有显著保护作用。
Objective To observe the effect of Guanxinping on myocardial ischemia. Methods The myocardial ischemia models were prepared by ligation 2mm below the first branch of left anterior descending coronary artery. The compound Danshen Dripping Pill was used as a positive control agent to observe whether Guanxinping has protective ischemic myocardium, reduced myocardial necrosis area, reduced myocardial The role of enzymes CK, CK-MB, LDH release. Results The area of ischemic myocardial necrosis was significantly reduced, and the release of CK, CK-MB, and LDH was significantly reduced. Conclusion Guanxinping has a significant protective effect on acute myocardial ischemia in dogs.