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目的:观察比较米索前列醇联合瑞芬太尼复合异丙酚用于无痛人工流产及异丙酚单独静脉注射行无痛人工流产的效果。方法:将瑞芬太尼复合异丙酚静脉注射联合米索前列醇用于无痛人工流产90例(观察组)、异丙酚单独静脉注射行无痛人工流产90例(对照组)对比,观察镇痛效果、手术时间、用药量、术中动体反应及宫颈松弛程度。结果:观察组具有镇痛效果好、起效快、手术时间短、宫颈松弛率高、用药少、无动体反应。结论:米索前列醇联合瑞芬太尼复合异丙酚应用于无痛人工流产具有效果好、不良反应少、安全性高等优点。
OBJECTIVE: To observe the effect of misoprostol combined with remifentanil and propofol on painless induced abortion and intravenous propofol alone. Methods: 90 cases of painless induced abortion (observation group) were treated with intravenous remifentanil combined with propofol and 90 cases of painless artificial abortion (control group) with propofol alone. Analgesic effect, operation time, dosage, intraoperative dynamic response and cervical relaxation were observed. Results: The observation group had good analgesic effect, fast onset of action, short operative time, high rate of cervical relaxation, less medication, and no response to the animals. Conclusion: The combination of misoprostol and remifentanil combined with propofol has the advantages of good effect, less adverse reactions, and higher safety in painless induced abortion.