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目的 :比较西沙必利与便秘通治疗婴幼儿便秘的疗效。方法 :西沙必利组 34例 (男性 18例 ,女性 16例 ,年龄 1.7a±s 1.3a)用西沙必利 0 .2mg·kg- 1,po ,tid ;便秘通组 34例 (男性 2 1例 ,女性13例 ,年龄 1.7a± 1.5a)用便秘通 3～ 5mL ,po ,tid。 2组疗程均为 7d。结果 :西沙必利组总有效率为 94 % ,便秘通组为 79% ,经Ridit分析检验 ,差异有显著意义 (P <0 .0 5) ,2组均未发现明显不良反应。结论 :西沙必利治疗婴幼儿便秘疗效优于便秘通。
Objective: To compare the efficacy of cisapride and constipation on constipation in infants and young children. Methods: Cisapride group of 34 patients (18 males, 16 females, age 1.7a ± s 1.3a) with cisapride 0.2 mg · kg-1, po, tid; constipation group of 34 patients (male 2 1 Cases, 13 females, age 1.7a ± 1.5a) with constipation 3 ~ 5mL, po, tid. 2 groups of treatment are 7d. Results: The total effective rate was 94% in cisapride group and 79% in constipation group. The Ridit analysis showed that the difference was significant (P <0.05). No significant adverse reactions were found in the two groups. Conclusion: Cisapride treatment of constipation in infants and children better than constipation.