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1904年Chauffard首先提出再生障碍性贫血(aplastic anemia,AA)的名称。即一组由于化学、物理、生物因素及不明原因所致的骨髓干细胞及造血微环境的损伤,以致红髓被脂肪髓代替,全血细胞减少的疾病。骨髓增生异常综合征(myelodysplastic syndrome,M D S)则是于1982年FAB协作组在观察大量病例基础上明确的,是一组以骨髓异常造血或无效造血、成熟障碍、外周血中有一系或多系血细胞减少及形态和功能异常为特征的血液病。AA
In 1904 Chauffard first proposed the name of aplastic anemia (AA). That is, a group of bone marrow stem cells and hematopoietic microenvironment damage due to chemical, physical, biological factors and unknown causes, so that the red pulp replaced by fat marrow, pancytopenia disease. Myelodysplastic syndrome (MDS) is based on the observation of a large number of cases in 1982 FAB collaboration group is a group of abnormal bone marrow or hematopoietic hematopoiesis, maturation disorder, one or more lines in the peripheral blood Hematocytopenia and morphological and functional abnormalities characterized by blood diseases. AA