论文部分内容阅读
T_3占优势 Graves 病患者其特征为,由于抗甲状腺药物治疗过程中,血清 T_3持续升高,T_4正常,T)_3/T_4比率(ng/μg)大于20。我们随访22例,接受药物治疗18～28个月,观察2年,16例复发。复发时间乎均停药8.8个月。其中8例复发者作甲状腺次全切除术,术后甲状腺功能恢复正常,血清 T_3/T_4比率均小于20。T_3占优势甲状腺机能亢进患者有较高的血清 TSH 受体抗体活性,与甲状腺 T_4 5′-脱碘酶活性有关.药物治疗缓解率低,以选用手术或同位素治疗为佳.
T_3 predominant Graves’ disease is characterized by an elevated serum T_3, normal T_4, and a T_ (3) / T_4 ratio (ng / μg)> 20 in antithyroid drugs. We followed up 22 cases, receiving drug treatment 18 to 28 months, observed 2 years, 16 cases of recurrence. Relapse time were almost discontinued for 8.8 months. Among them, 8 cases of recurrence were treated by subtotal thyroidectomy, and thyroid function returned to normal after operation. The T_3 / T_4 ratios of serum were less than 20. T_3 dominant thyroid hyperthyroidism patients with high serum TSH receptor antibody activity, and thyroid T_4 5’-deiodinase activity related to the drug treatment response rate is low, the choice of surgery or isotope therapy is better.