姊妹染色单位互换(SCE)是近年来发展起来的细胞遗传学技术之一。其产生原理可能是由于受损伤的染色体发生切割、修复、重组所致。目前国内外利用此技术深入研究有丝分裂中染色体复制、染色体的组成,DNA 的伤损、修复能力,以及致突变和致癌物对染色体的损伤等。由于 SCE 技术比较敏感,且简便易行。我们试图利用此方法合并染色体常规检查对宫颈癌患者的早期诊断进行探讨。 Sister chromatid exchange (SCE) is one of the cytogenetics developed in recent years. Its production principle may be due to damaged chromosomes occur cutting, repair, recombination caused. At present, this technique is used both at home and abroad to deeply study chromosome duplication, chromosome composition, DNA damage and repair ability in mitosis, as well as mutagenesis and carcinogen damage to chromosomes. As SCE technology is more sensitive and simple. We tried to use this method combined with routine chromosome examination of cervical cancer in patients with early diagnosis to explore.