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对９６例成人急性白血病（其中急淋３２例，急非淋６４例）作体外细胞毒试验，发现急淋和急非淋白血病细胞对柔红霉素（Ｄ）、长春新碱（Ｖ）、氨甲喋呤（Ｍ）、高三尖杉酯碱（Ｈ）、阿糖胞苷（Ａ）及ＶＰ１６～２１３敏感性无统计学差异（Ｐ＞０．０５），临床常用化疗方案（ＶＤＰ、ＤＡ、ＨＯＡＰ）细胞杀伤率积分与骨髓原始细胞下降指数（ＭＢＤＩ）和完全缓解（ＣＫ）率呈正相关，≥９分患者ＣＲ率明显高于＜９分者（Ｐ＜０．０１）。因此作者建议对初治急性白血病应先作体外细胞毒试验，以选择敏感药物组成联合化疗方案。
In 96 cases of adult acute leukemia (acute lymphadenopathy in 32 cases, acute non-lymphatic 64 cases) for in vitro cytotoxic test found that acute lymphoblastic and acute non-leukemia cells daunorubicin (D), vincristine (V) The sensitivity of methotrexate (M), homoharringtonine (H), cytarabine (A) and VP16-213 were not significantly different (P> 0.05) .The routine chemotherapy regimen (VDP, DA and HOAP) The cell kill rate integral was positively correlated with the bone marrow blast index (MBDI) and complete remission (CK) rate. The CR rate of ≥9 was significantly higher than <9 (P <0.01). Therefore, the authors suggest that the initial treatment of acute leukemia should be used in vitro cytotoxic test in order to select the combination of sensitive drug combination chemotherapy.