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目的:了解我院药品不良反应(ADR)发生特点,促进临床合理用药。方法:对我院2008年收集到的118例ADR报告分别从患者性别、年龄、给药途径、药品种类及临床表现等方面进行统计、分析。结果:抗感染药物引发ADR居首位(38.14%),中药制剂次之(28.81%);60岁以上患者ADR发生率最高(31.35%);静脉给药是引发ADR的主要给药途径(88.14%);ADR最常见的临床表现为皮肤及其附件损害(41.45%),严重ADR有10例。结论:应充分重视ADR的监测与报告,加强安全、合理用药,减少或避免ADR的发生。
Objective: To understand the characteristics of adverse drug reaction (ADR) in our hospital and promote clinical rational use of drugs. Methods: A total of 118 cases of ADR collected in our hospital in 2008 were analyzed statistically from patient’s gender, age, route of administration, type of drug and clinical manifestations. Results: ADR was the highest (38.14%) induced by anti-infective drugs and followed by traditional Chinese medicine (28.81%). The incidence of ADR was the highest in patients over 60 years old (31.35%). Intravenous administration was the main route of ADR %). The most common clinical manifestations of ADR were skin and its accessory damage (41.45%) and severe ADR in 10 cases. Conclusion: Adequate attention should be paid to the monitoring and reporting of ADR, to strengthen the safety and rational use of drugs to reduce or avoid the occurrence of ADR.