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本文根据 Chetty 的方法加以改良,复制急性出血坏死型胰腺炎(AHNP)动物模型。观察胰腺和胰外主要脏器的损害情况,其发生率;急性胰腺炎(AP)100%、AHNP80%、肺损害56%、肾损害52%、肝损害36%,心损害24%。通过光镜和电镜形态学观察,探讨 AHNP 并发症产生机理和防治依据。
This article was modified according to Chetty’s method to replicate acute hemorrhagic necrotizing pancreatitis (AHNP) animal model. Acute pancreatitis (AP) 100%, AHNP 80%, lung damage 56%, kidney damage 52%, liver damage 36%, heart damage 24%. Morphological observation by light and electron microscopy to explore the mechanism of AHNP complications and prevention basis.