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目的:提高膀胱非移行细胞肿瘤的诊断水平,探索治疗方法。方法:回顾性总结近10 a收治的膀胱非移行细胞肿瘤21例,采取膀胱部分切除和膀胱全切除,手术前后配合髂内动脉灌注化疗和术后膀胱内灌注化疗。结果:21例获得1 a~5 a随访,6例良性肿瘤术后无复发;15例恶性肿瘤,术后死亡6例(4例死于肿瘤转移,2例死于心、肾疾病),9例已平均无瘤存活45.3个月,3 a存活率66.6 %。结论:膀胱非移行细胞肿瘤以膀胱内肿块、血尿、膀胱刺激征为主要临床表现。治疗上以手术为主,配合动脉化疗可提高疗效。
Objective: To improve the diagnosis of non-metastatic bladder tumor and to explore the therapeutic method. Methods: Twenty-one cases of non-metastatic bladder cancer were retrospectively reviewed. Partial bladder resection and total bladder resection were performed. The patients were treated with internal iliac artery infusion chemotherapy and intra-bladder infusion chemotherapy before and after operation. Results: Twenty-one patients were followed up from 1 year to 5 years. No recurrence was found in 6 cases of benign tumors. Of the 15 cases of malignant tumors, 6 died (4 died of tumor metastasis and 2 died of heart and kidney disease), 9 Cases had an average tumor-free survival of 45.3 months, 3-year survival rate of 66.6%. Conclusion: Bladder non-transitional cell tumor with bladder mass, hematuria, bladder irritation as the main clinical manifestations. The main treatment for surgery, with arterial chemotherapy can improve the curative effect.