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葡萄糖是维持细胞能量代谢和生命活动的重要原料。葡萄糖是一种极性分子,不能以自由扩散的方式进入细胞,除了小肠和肾小管可以通过主动转运方式吸收葡萄糖外,大部分组织包括胎盘的细胞都必须通过镶嵌在细胞膜上的载体蛋白质-葡萄糖转运体(GLUTs)介导的易化扩散来摄入葡萄糖。葡萄糖是胎儿生长发育的基础营养物质,因此,葡萄糖从母体向胎儿的跨胎盘转运对胎儿的生长发育至关重要。本文将对由胎盘GLUT介导的葡萄糖跨胎盘转运及其相
Glucose is an important raw material for the maintenance of cellular energy metabolism and life activities. Glucose is a polar molecule that can not enter cells in a freely diffusive way except that the small intestine and tubules can absorb glucose through active transport. Most tissues, including the placenta, must pass through the carrier protein-glucose Glucose is uptake by GLUTs-mediated facilitated diffusion. Glucose is the basis of fetal growth and development of nutrients, therefore, from the mother to the fetus transplacental transplacental growth and development of the fetus is crucial. This article will address the GLUT-mediated glucose transplacental transport and its phase