2型糖尿病患者β细胞功能下降,胰岛素分泌不足,早期应用胰岛素可保护和恢复β细胞功能,但并非只有胰岛素才可减低糖毒性,改善胰岛素分泌,任何方法只要能有效降低血糖,纠正高血糖毒性都有可能显著改善β细胞分泌功能,每天多次胰岛素注射患者依从性差,综合社会经济效益低;磺脲类 Type 2 diabetes patients with decreased beta cell function, lack of insulin secretion, the early application of insulin can protect and restore beta cell function, but not only insulin can reduce glucose toxicity, improve insulin secretion, any method as long as it can effectively reduce blood glucose and correct hyperglycemic toxicity Are likely to significantly improve the β-cell secretion, multiple daily injections of insulin in patients with poor compliance, low overall socio-economic benefits; sulfonylureas