实验采用外周血淋巴细胞ANAE活性和脾细胞E玫瑰花结反应作为指标,对H615带瘤小鼠的细胞免疫功能进行了动态观察。结果表明,带瘤动物外周血淋巴细胞的ANAE阳性率和T/B比值,以及脾细胞的E—RFC阳性率在H615生长的潜伏期均无明显变化,进入缓慢生长期后则均明显升高,处于H615的快速生长期时均显著降低,且外周血淋巴细胞ANAE阳性率和脾细胞E—RFC阳性率的变化时相,规律比较一致。 In the experiment, the cellular immune function of H615 tumor-bearing mice was dynamically observed by using ANAE activity of peripheral blood lymphocytes and E rosette reaction of spleen cells as indicators. The results showed that the ANAE-positive rate and T/B ratio of peripheral blood lymphocytes in tumor-bearing animals and the E-RFC-positive rate of spleen cells did not change significantly in the incubation period of H615, and they all increased significantly after entering the slow-growing period. In the rapid growth phase of H615, it was significantly reduced, and the positive rate of ANAE in peripheral blood lymphocytes and the frequency of E-RFC positive rate in spleen cells were similar.