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关于ras基因及其产物P21蛋白的致癌作用是近年来国内外肿瘤研究的热点之一，目前已发现许多恶性肿瘤中有P”蛋白的过量表达。我们应用免疫组化方法分别检测P’‘蛋白和增殖细胞核抗原（PCNA）在胃癌中的表达情况以探讨P’‘的表达程度与胃癌的类型、恶性度及预后的关系。1材料?
The oncogenic effect of ras gene and its product P21 protein is one of the hot spots in tumor research at home and abroad in recent years. It has been found that many malignant tumors have overexpression of P” protein. We use immunohistochemistry to detect P′′ protein respectively. Expression of proliferating cell nuclear antigen (PCNA) in gastric cancer to investigate the relationship between the degree of P’’expression and the type, malignancy, and prognosis of gastric cancer.1 Materials?