目的了解东海县手足口病流行病学特点,为制定防控措施提供科学依据。方法采用描述流行病学方法,对2012年东海县传染病报告信息管理系统的手足口病疫情资料进行分析。结果 2012年全县共报告手足口病病例357例,发病率为30.25/10万;男性39.27/10万,女性20.48/10万,性别差异有统计学意义(P<0.01)。病例主要集中在4~7月,占81.79%,呈明显的季节性特点;全县21个乡镇均有病例发生;发病年龄最小的5个月、最大的12岁,3岁及以下幼儿占病例总数的90.76%。实验室确诊41例,其中感染肠道病毒71型16例,占39.03%,Cox A16型18例,占43.90%,其他肠道病毒7例,占17.07%。结论 2012年东海县手足口病发病以幼儿为主,应加强疫情监测和宣传教育力度,做好病原学检测,防止其暴发流行。 Objective To understand the epidemiological characteristics of hand, foot and mouth disease in Donghai County and provide a scientific basis for making prevention and control measures. Methods Descriptive epidemiological methods were used to analyze the hand, foot and mouth disease data of the infectious disease reporting information management system in Donghai County in 2012. Results A total of 357 HFMD cases were reported in the county in 2012, with an incidence rate of 30.25 per 100 000. There were 39.27 per 100 000 males and 20.48 females per 100 000 females. There was a statistically significant difference in gender (P <0.01). The cases were mainly from April to July, accounting for 81.79%, showing obvious seasonal features. Cases were reported in 21 towns and townships throughout the county; the youngest was 5 months and the largest 12-year-old and 3-year-old children accounted for the cases 90.76% of the total. Laboratory confirmed 41 cases, including infection of enterovirus 71 in 16 cases, accounting for 39.03%, 18 cases of Cox A16 type, accounting for 43.90%, 7 cases of other enterovirus, accounting for 17.07%. Conclusion The occurrence of hand, foot and mouth disease in Donghai County in 2012 is mainly young children. It is necessary to strengthen the monitoring and publicity and education of epidemic situation and conduct the etiological detection to prevent its outbreak.