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恶性肿瘤患者由于正常组织屏障的破坏,免疫抑制治疗(药物、或药物加放射)与由于肿瘤所致的机体内在免疫缺陷,容易引起感染。随着肿瘤治疗的发展,恶性肿瘤患者生存期得到延长,感染已成为最常见的死亡原因。本文讨论恶性肿瘤患者抗菌药物治疗的现代概念。一、感染的危险因素恶性肿瘤的局部浸润、转移、外科手术、异物(静脉插管、导尿管、气管插管)、褥疮均可造成皮肤、粘膜的损伤,侵入的细菌以
Patients with malignant tumors are prone to infection due to the destruction of normal tissue barriers, immunosuppressive therapy (drugs, or drugs plus radiation) and intrinsic immune defects in the body due to tumors. With the development of cancer treatment, the survival of patients with cancer has been extended, the infection has become the most common cause of death. This article discusses the modern concept of antimicrobial therapy in patients with malignancies. First, the risk of infection Local invasion of malignant tumors, metastasis, surgery, foreign body (intravenous catheter, catheter, tracheal intubation), bedsores can cause skin and mucous membrane damage, invasive bacteria to