Heparin therapy for preeclampsia has been reportedfrequently.Most of the authors used heparin toprevent thrombosis and achieved good results. But itsmechanism is not clear.4 Here we describe a case ofsevere early-onset preeclampsia complicated withhypercoagulable state, fetal growth restriction, andtwin-twin transfusion syndrome, that responded well toheparin.CASE REPORTA 32-year-old woman at the 31st gestational weekcomplaining of high blood pressure, edema of the lower The mechanism of preeclampsia has been reported as closely. Host of the authors used heparin toprevent thrombosis and achieved good results. But its mechanism of not clear 4 Here we describe a case of early early-onset preeclampsia complicated with hypercoagulable state, fetal growth restriction, andtwin-twin transfusion syndrome, that responded well to heparin. CASE REPORTA 32-year-old woman at the 31st gestational week complaining of high blood pressure, edema of the lower