肺纤维化(pulmonary fibrosis,PF)是由多种原因引起慢性肺疾病的共同结局,是呼吸衰竭的主要病理基础,其病理特点是肺部炎症导致肺泡持续性损伤及细胞外基质的反复破坏修复、重建和过度沉积。随着对肺纤维化发生机制研究的不 Pulmonary fibrosis (PF) is a common outcome of chronic lung diseases caused by many causes and is the main pathological basis of respiratory failure. The pathological features of lung fibrosis are persistent lung injury and repeated destruction of extracellular matrix , Reconstruction and over-deposition. With the mechanism of pulmonary fibrosis research does not