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肠道小孢子虫病是免疫功能受损患者慢性腹泻、营养不良、消瘦的重要原因,目前尚无有效的治疗方法,夫马洁林(Fumagillin)是一种抗生素,用它来治疗肠道阿米巴病已有40多年的历史。初步研究表明夫马洁林能治疗人免疫缺陷病毒感染患者的小孢子虫病,本实验旨在通过随机双盲对照试验,探索夫马洁林是否对免疫受损患者感染的小孢子虫病有效。方法 选取12例患有慢性肠道小孢子虫病且免疫功能受损的患者为研究对象,随机分
Intestinal microsporidiosis is an important cause of chronic diarrhea, malnutrition and emaciation in immunocompromised patients. There is currently no effective treatment. Fumagillin is an antibiotic used to treat intestinal amoeba The disease has more than 40 years of history. Preliminary studies have shown that fumagillin can treat microsporidiosis in patients infected with human immunodeficiency virus. This experiment aimed to investigate whether fumagillin is effective against microsporidiosis in patients with immunocompromised lesions by a randomized double-blind controlled trial. Methods Twelve patients with chronic intestinal microsporidiosis and impaired immune function were selected as study subjects and randomized