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目的观察热毒宁注射液辅助治疗恶性胸腔积液(MPE)的临床疗效。方法选取2013年1月—2015年6月江苏大学附属金坛医院呼吸内科收治的MPE患者60例。采用随机数字表法将患者分为观察组和对照组,各30例。对照组给予胸腔置管引流胸腔积液、胸腔内注射顺铂及白介素2等治疗。观察组在对照组的基础上给予静脉滴注热毒宁注射液。比较两组患者发热率、临床疗效及KPS评分改善情况。结果观察组发热率低于对照组,临床疗效、KPS评分改善率及总有效率高于对照组(P<0.05)。结论热毒宁注射液辅助治疗MPE的疗效确切。
Objective To observe the clinical efficacy of Renduining injection in the treatment of malignant pleural effusion (MPE). Methods Sixty patients with MPE admitted to Department of Respiratory Medicine, Jintan Hospital, Jiangsu University from January 2013 to June 2015 were selected. The patients were divided into observation group and control group by random number table method, each 30 cases. The control group was given thoracic tube drainage drainage, intrapleural injection of cisplatin and interleukin 2 and other treatment. The observation group was given intravenous injection of Renduining injection on the basis of the control group. The rates of fever, clinical efficacy and improvement of KPS score were compared between the two groups. Results The fever rate in observation group was lower than that in control group. The clinical curative effect, improvement rate of KPS score and total effective rate were higher than those in control group (P <0.05). Conclusion Revedynin injection adjuvant treatment of MPE is effective.