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23只新西兰兔分为热射病组(n=11)、降温组(n=6)和对照组(n=6),研究热射病发生及经腹腔给予冷液降温过程中,直肠(Tr)、食道(Te)和下丘脑(Th)温度的动态变化。结果表明,Tr为42.5℃以前,Th高于Tr和Te;热射病休克发生时,Tr高于Te和Th。Tr、Te和Th随着温度的升高,上升速度减慢;高于41.5℃时,Te和Th上升速度显著减慢(P<0.05);高于42.5℃时,Th上升速度较前更慢(P<0.01)。与对照组相比,降温组动物存活时间显著延长(P<0.001),体温显著降低(P<0.001);在降温的开始20分钟内,Tr、Te和Th都急剧下降,Tr和Te出现明显降温高峰;第20分钟至动物死亡时,Tr和Te的下降速度比Th显著减慢(P<0.01)。提示:热射病及经腹腔降温过程中,深部体温的升降速度并不完全一致,腹腔冷液降温是热射病紧急情况下迅速降低体温的较好方法。
Twenty-three New Zealand rabbits were divided into two groups: n = 11, n = 6, n = 6 and control group (n = 6) ), Esophagus (Te) and hypothalamus (Th). The results showed that Th was higher than Tr and Te before Tr was 42.5 ℃, and Tr was higher than that of Te and Th when heat shock was induced. The rising speed of Tr, Te and Th slowed down with the increase of temperature. When the temperature was higher than 41.5 ℃, the rising speed of Te and Th slowed down significantly (P <0.05); when it was higher than 42.5 ℃, Th The rate of increase was slower than before (P <0.01). Compared with the control group, the survival time of the animals in the cooling group was significantly longer (P <0.001) and the body temperature was significantly lower (P <0.001). Tr, Te and Th both dropped sharply within the first 20 minutes of cooling, while Tr And Te appeared obvious cooling peak; the first 20 minutes to the death of animals, Tr and Te decline rate was significantly slower than Th (P <0.01). Hint: In the course of thermal and intraperitoneal cooling, the speed of deep body temperature rise and fall is not exactly the same. The cooling of abdominal cavity cold fluid is a good way to reduce body temperature rapidly in the event of an emergency of fever.