二茂铁基苯甲酸四乙酰葡萄糖酯的合成及其抗贫血活性

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Three tetraacetyl glucosyl esters of the ferrocenyl benzoic acids(compounds Ⅱ o,Ⅱ m,Ⅱ p) have been synthesized using a phase transfer catalyst(CTAB) in dichloroethane/water at 50 ℃. Their structures have been confirmed by elemental analysis, IR, 1H NMR and MS. The compounds were found to have antianemic activity. The RBC and HB values of the tested anemic rats were increased by 72 0% and 126 4%, respectively after abdomen injection. Three tetraacetyl glucosyl esters of the ferrocenyl benzoic acids (compounds Ⅱ o, Ⅱ m, Ⅱ p) have been synthesized using a phase transfer catalyst (CTAB) in dichloroethane / water at 50 ° C. Their structures have been confirmed by elemental analysis, IR, 1H NMR and MS. The compounds were found to have antianemic activity. The RBC and HB values ​​of the tested anemic rats were increased by 72 0% and 126 4%, respectively after abdomen injection.
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