论文部分内容阅读
本文应用放射免疫测定方法,测定22例正常人和29例充血性心衰病人血浆心钠素浓度,其中17例病人在治疗过程中进行了重复测定。结果表明心衰病人心钠素水平(673±205pg/ml)显著高于正常人(105±23pg/ml)(P<0.05),但有14例严重心衰病人心钠素水平降低。血浆心钠素浓度随着心衰改善丽显著下降。动态观察心钠素水平变化对于判断心衰程度和预后及估价治疗反应可能有一定意义。
In this paper, radioimmunoassay was used to determine plasma atrial natriuretic peptide concentrations in 22 normal subjects and 29 congestive heart failure patients. Seventeen patients were measured repeatedly during the course of treatment. The results showed that the level of atrial natriuretic peptide in heart failure patients (673 ± 205pg / ml) was significantly higher than that in normal people (105 ± 23pg / ml) (P <0.05). However, the level of atrial natriuretic peptide decreased in 14 patients with severe heart failure. Plasma atrial natriuretic peptide decreased significantly with improvement of heart failure. Dynamic observation of changes in the level of atrial natriuretic peptide in determining the degree of heart failure and prognosis and evaluation of treatment response may have some significance.